Faculty Staff / Section of Genetics, Cell & Developmental Biology
Associate Professor in Environmental Mutagenesis

Office location: 2nd Floor (Β/Μ 209)
Email: dvlastos@upatras.gr
Telephone: +30 2610 969239 (office) / +30 2610 996150 (Lab.)


  • BSc in Biology, Department of Biology, University of Patras
  • PhD in Biology, Department of Biology, University of Patras

Educational activities

Undergraduate courses:

  • Fundamental Principles in Cell Biology – Teaching,
  • Genetics,
  • General Biology

Postgraduate courses:

  • Environmental Mutagenesis,
  • Ecological Genetics & Ecotoxicology

Research interests

  • Genotoxicological effects of various factors such as radiation, pesticides, pharmaceuticals compounds, nanoparticles, newly synthesized chemicals, environmental pollutants, municipal and industrial waste (before and after treatment) on various organisms including human.
  • Cytogenetic effects on human genetic material as a result of occupational exposure to various pollutants.
  • Detection of xenobiotic agents in environmental samples (rainwater, soil organic matter, surface water of lakes and rivers) and assessment of their genotoxicological effects on various organisms including human.
  • Analysis and assessment of the effect of various environmental factors on the expression of selected genes.
  • Extraction, isolation and characterization of plant extracts
  • Determination of antigenotoxic (antimutagenic) activity of plant extracts in the genetic material of various organisms including human.

Representative Publications

  • Demsia , Vlastos D., Goumenou M., Matthopoulos D.P. (2007). Assessment of Imidacloprid and Metalaxyl genotoxicity on cultured human lymphocytes and rat bone marrow, Mutation Research-Genetic Toxicology and Environmental of Mutagenesis, 634, 32-39.
  • Vlastos D., Moshou H., Epeoglou K. (2010) Evaluation of genotoxic effects of semicarbazide on cultured human lymphocytes and rat bone marrow, Food and Chemical Toxicology, 48, 209-214.
  • Vlastos D., Ntinopoulos A. (2011). Induction of micronuclei on Greek hairdressers occupationally exposed to chemical mixtures, Environmental Toxicology, 26 (5), 506-514.
  • Vlastos D., Mademtzoglou D., Drosopoulou E., Efthimiou I., Chartomatsidou T., Pandelidou C., Astyrakaki M., Chalatsi E., Mavragani-Tsipidou P. (2013). Evaluation of the genotoxic and antigenotoxic effects of Chios mastic water by the in vitro micronucleus test on human lymphocytes and the in vivo wing somatic test on Drosophila, PLoS ONE 8(7): e69494. doi:10.1371/journal.pone.0069494.
  • Chowdhury A.K.M.M.B., Konstantinou F., Damati A., Akratos C.S., Vlastos D., Tekerlekopoulou A.G., Vayenas V. (2015) Is physicochemical evaluation enough to characterize olive mill waste compost as soil amendment? The case of genotoxicity and cytotoxicity evaluation, Journal of Cleaner Production, 93, 94-102.
  • Charalampous N., Kindou A., Vlastos D., Tsarpali V., Antonopoulou M., Konstantinou I.K., Dailianis S. (2015) A multidisciplinary assessment of river surface water quality in areas heavily influenced by human activities, Archives of Environmental Contamination and Toxicology, 69(2), 208-222.
  • Vidali M-S., Bletsa E., Kouloumpis A., Skoutelis C.G., Deligiannakis Y., Gournis D., Vlastos D. (2016) Induction of Micronuclei by Multi-Walled Carbon Nanotubes interacting with Humic Acids in cultured human lymphocytes, Environmental Science: Nano, 3, 74 – 84.
  • Vlastos D., Antonopoulou M., Konstantinou I.K. (2016) Evaluation of toxicity and genotoxicity of 2-Chlorophenol on bacteria, fish and human cells, Science of the Total Environment, 551-552, 649-655.
  • Vlastos D., Dailianis S., Kindou A., Antonopoulou M., Gianni A., Zacharias I. (2017) Assessing the environmental/human risk of potential genotoxicants in water samples from lacustrine ecosystems: the case of lakes in Western Greece, Science of the Total Environment, 574, 246-252.
  • Tsarpali V., Goutas A., Karyda A., Efthimiou I., Antonopoulou M., Drosopoulou E., Vlastos D., Konstantinou I., Mavragani-Tsipidou P., Dailianis (2017) The role of acetone in the [omim] [BF4]-mediated adverse effects on tissues of mussels, human lymphocytes and the fruit fly Drosophila melanogaster, Journal of Hazardous Materials, 333, 339-347.
  • Drosopoulou E., Vlastos D., Efthimiou I., Kyrizaki P., Tsamadou S., Anagnostopoulou M., Kofidou D., Gavriilidis M., Mademtzoglou D., Mavragani-Tsipidou P. (2018) In vitro and in vivo evaluation of the genotoxic and antigenotoxic potential of the major Chios mastic water constituents, Scientific Reports, 8(1), 12200.
  • Vlastos D., Antonopoulou M., Lavranou A., Efthimiou I., Dailianis S., Hela D., Lambropoulou D., Paschalidou A.K., Kassomenos (2019) Assessment of the toxic potential of rainwater precipitation: First evidence from a case study in three Greek cities, Science of the Total Environment, 648, 1323-1332.
  • Αntonopoulou M., Thoma A., Konstantinou F., Vlastos D., Hela D. (2020) Assessing the human risk and the environmental fate of pharmaceutical Tramadol, Science of the Total Environment, 707, 135396.
  • Efthimiou I., Georgiou Y., Vlastos D., Dailianis S., Deligiannakis Y. (2020) Assessing the cyto-genotoxic potential of model zinc oxide nanoparticles in the presence of humic-acid-like-polycondensate (HALP) and the leonardite HA (LHA), Science of the Total Environment, 721, 137625.
  • Moshou H., Karakitsou A., Yfanti F., Hela D., Vlastos D., Paschalidou A.K., Kassomenos P., Petrou I. (2020) Assessment of genetic effects and pesticide exposure of farmers in NW Greece, Environmental Research, 186, 109558.
  • Chatzimpaloglou Α., Christophoridis C., Fountoulakis I., Antonopoulou M., Vlastos D., Bais A., Fytianos (2021) Photolytic and photocatalytic degradation of antineoplastic drug irinotecan. Kinetic study, identification of transformation products and toxicity evaluation, Chemical Engineering Journal, 405, 126866.
  • Efthimiou I., Kalamaras G., Papavasileiou K., Anastasi-Papathanasi N., Georgiou Y., Dailianis S., Deligiannakis Y., Vlastos (2021) ZnO, Ag and ZnO-Ag nanoparticles exhibit differential modes of toxic and oxidative action in hemocytes of mussel Mytilus galloprovincialis, Science of the Total Environment, 767, 144699.
  • Vidali M-S., Dailianis S., Vlastos D., Georgiadis P. (2021) PCB cause global DNA hypomethylation of human peripheral blood monocytes in vitro, Environmental Toxicology and Pharmacology, 87, 103696.
  • Kalamaras G., Kloukinioti M., Antonopoulou M., Ntaikou I., Vlastos D., Eleftherianos A., Dailianis (2021) The potential risk of electronic waste disposal into aquatic media: the case of personal computer motherboards, Toxics, 9(7), 166.
  • Dailianis S., Charalampous N., Giokas S., Vlastos D., Efthimiou I., Dormousoglou M., Cocilovo C., Faggio C., Shehu A., Shehu J., Lyberatos G., Ntaikou I. (2021) Chemical and biological tracking in decentralized sanitation systems: the case of artificial constructed wetlands, Journal of Environmental Management, 300, 113799.